gMote - Control your computer with gestures
gMote allows you to record gestures (mouse motions) and assign them to frequently performed tasks. Use gestures to bring up programs, websites, control your browser, media player, clipboard and much more. You can even assign your own key combinations to a gesture - make text bold by drawing a “b”, lock your computer with an “L” - it’s fully customisable. Watch Gmote in Action
Works fine on Windows XP and Windows Vista gMote is freeware. Download from here.

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